Tamiflu metabolites measured in Japanese sewage discharge, River WaterIn a study published 24th September ahead of print in the peer-reviewed journal Environmental Health Perspectives , measured researchers oseltamivir carboxylate , the active metabolite of the popular anti – flu drug Tamiflu , from in samples of wastewater discharge and river water near Kyoto City gathered during Japan’s 2008-2009 flu season.
Of resistant levels strongly discharge samples, depending on the type of waste water purification methods used with a much lower peak concentration measured at the outlet from an STP that used ozonation as additional treatment.. Other authors of the paper are Norihide Nakada, Naoyuki Yamashita and Hiroaki Tanaka. This study was partly supported by the Ministry of Land, Infrastructure, Transport and Tourism of Japan and the Japan Society for the Promotion of Science supported.
OC concentrations were highest in all samples taken during the height of the seasonal flu, with the highest concentration, 3 nanograms per liter measured in the effluent from a conventional activated sludge-based STP. [...]